Oxidative stress also triggers certain cellular events mediated by transcription factors such as ROS upgrade transcription factor activator protien-1 (AP-1) that increases matrix metalloprotienase (MMP) production, leading to collagen breakdown. The harmful effects of ROS occur as direct chemical alterations of the cellular DNA, the cell membrane and the cellular proteins, including collagen. These radicals have a potential to start chain or cascade reactions that damage the cells.
#Vitamin c serum skin
C and photoprotectionĪs mentioned above, the exposure of skin to UV light generates ROS. UV light, reactive oxygen species (ROS) and skin damage - Vit. The use of topical ascorbic acid is therefore favored in the practice of dermatology. C in the skin is inadequate when it is administered orally. C in the gut is limited by an active transport mechanism and hence a finite amount of the drug is absorbed despite high oral dosage. However, only LAA is biologically active and thus useful in medical practice. These are essentially isomeric molecules and are mutually interchangeable. C is found in equal parts as LAA and D-ascorbic acid. L-ascorbic acid (LAA) is the chemically active form of Vit. C molecule from red peppers and identifying its role in Scurvy. Albert Szent Goyrgi was awarded the Nobel Prize for his work in isolating the Vit. C-rich foods like lemons were carried by sailors on long journeys to avoid Scurvy, a disease of bleeding gums. C hence, they must acquire it from natural sources such as citrus fruits, green leafy vegetables, strawberries, papaya and broccoli.
Humans and certain other vertebrates lack the enzyme L-glucono-gamma lactone oxidase required for in vivo synthesis of Vit. Most plants and animals are able to synthesise Vit. C) is one of the naturally occurring antioxidants in nature. Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis. Shaw G, Lee-Barthel A, Ross ML, Wang B, Baar K. Alkyl esters of L-ascorbic acid: Stability, surface behaviour and interaction with phospholipid monolayers. Mottola M, Vico RV, Villanueva ME, Fanani ML. Flow injection analysis of ascorbyl glucoside in cosmetics by a disposable printed-circuit board waste modified electrode.
Niacinamide: A B vitamin that improves aging facial skin appearance. Available from: īissett DL, Oblong JE, Berge CA. Leading esthetician Samantha Appel tells us that mixing B vitamins (like niacinamide) with vitamin C is a beneficial pairing and will “soothe, brighten and refine the skin’s appearance”.Īlternatively, Appel explains that AHAs and BHAs (such as glycolic, salicylic, or lactic acids) will potentially react with your vitamin C serum, so they are best left for the evening (and don’t mix products containing the two).
Some forms are prone to oxidation (L-ascorbic acid especially), so if your product takes on a yellow-ish appearance once opened, chances are it’s lost its efficacy. Some of the most effective ones to look out for are L-ascorbic acid, ascorbyl 6 palmitate, disodium isostearyl 2-0 L-ascorbyl phosphate, tetris palmitoyl ascorbic acid, ascorbic acid sulfate, magnesium ascorbyl phosphate, and ascorbyl glucoside2. Vitamin C in its pure form is L-ascorbic acid, but when it comes to topical products it can vary. What to Look for in a Drugstore Vitamin C Serum The Type of Vitamin C Also honorable mention to Appel’s favorite Biologi Radiance Serum (view at Biologi) for its minimal ingredients and skin-boosting effect. Your ideal drugstore vitamin C serum will depend on your skin type and condition, but team Byrdie unanimously agrees that the Versed Stroke of Brilliance Vitamin C Serum (view at Versed) and the Avene A-Oxitive Antioxidant Defense Serum (view at Amazon) are a bang for your buck. Keep scrolling to shop the best and brightest drugstore vitamin C serums on the market. But we get the price can sometimes be off-putting (it is a very popular active ingredient, after all), so we’ve taken the liberty of compiling some drugstore vitamin C serum favorites that deliver all the glowy skin goodness minus the price tag. Serums are generally thinner and more concentrated as far as skincare products go, which is why it makes a great vehicle for vitamin C. Vitamin C is a naturally-occurring antioxidant, but interestingly humans lack the enzyme needed for its synthesis which is why we rely on food, and in this instance topical products, to experience the benefits.
#Vitamin c serum free
A powerful antioxidant, vitamin C essentially works by neutralizing free radicals from the environment, assisting in the repair of damaged cells, improving collagen production, skin elasticity, signs of photoaging (like pigmentation), and barrier function. Anyone interested in skincare (slowly raises hand) has no doubt heard about the benefits of vitamin C serums.